Toxicologic Pathology: A Primer 1st Edition

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Toxicologic Pathology: A Primer - Your Essential Guide to Nonclinical Safety This book is a practical, easy-to-use reference designed to be the first basic overview covering the field of toxicologic pathology . It contains the core, underlying principles of the discipline, making it valuable to the veterinary pathology student considering a career in the field and serving as a succinct refresher for the seasoned toxicologic pathologist. Key Features Core Principles and Concepts: The book introduces the basic, underlying principles of toxicologic pathology, including an overview chapter covering the field and a "concept" chapter describing its role in drug development . Systematic Organization: The Primer is arranged as chapters presenting each major organ system . These chapters provide histopathologic descriptions of lesions observed in toxicity studies and testing of chemicals that may negatively impact the environment. Lesion Significance: Each organ system chapter provides additional information related to a particular lesion to aid the reader in better understanding its toxicologic significance relative to human risk . Chapter Structure: Each organ system chapter is consistently structured, containing: A brief introduction. A succinct description of the anatomy and physiology of the system. Descriptions of the most important pathological lesions . Differential diagnoses . Biological consequences, pathogenesis, and/or mechanism of lesion formation . Associated clinical pathology correlates . Broad Audience: This Primer is useful for nonclinical safety scientists (like study directors and senior toxicology report reviewers), scientific management of Contract Research Organizations (CROs), and students .

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